| presynaptic terminals: from basic biology to dysregulation in brain disease | Medical Faculty Heidelberg | Institute of Anatomy and Cell Biology | |
| translational neuroscience | Heidelberg University Hospital | Institute of Human Genetics | |
| neuronal calcium signaling; synaptic activity-driven transcription, NMDA receptor functions in survival and cell death, neuroprotection, drug discovery | | Institute of Neurobiology | |
| magnetic resonance neurography | Heidelberg University Hospital | | |
| molecular neurogenetics, disease modelling, neurodevelopmental disorders, iPSC-derived neuronal stem cells and neurons | Heidelberg University Hospital | Institute of Human Genetics | |
| | | University Hospital Heidelberg | |
| impact of social relationships on health | Heidelberg University Hospital | Institute for Medical Psychology | |
| retinal degeneration, autoimmune disease, neuroinflammation, multiple sclerosis | Heidelberg University Hospital | | |
| pathophysiology and pathogenesis (risk & resilience) in major psychiatric disorders; neurofunctional connectivity magnetic resonance imaging | Heidelberg University Hospital | Center for Psychosocial Medicine | |
| immunobiology of brain tumors, drug screening, personalized medicine, tumor organoids and other patient-derived disease models | Heidelberg University Hospital | | |
| protein quality control and neurodegeneration | | Center for Molecular Biology | |
| molecular cell biology of synapses | Medical Faculty Heidelberg | Institute for Anatomy and Cell Biology | |
| neuropaediatrics and metabolic medicine | Heidelberg University Hospital | Neuropediatics and Metabolic Medicine | |
| molecular mechanisms underlying chronic pain | Medical Faculty Heidelberg | Institute of Pharmacology | |
| molecular neurogenetics, gliobastoma, metabolism, organoid, drug development | German Cancer Research Center | | |
| cell fate engineering, disease modeling, transcriptional networks, stem cell biology, cancer neuroscience | German Cancer Research Center | | |
| psychiatry and psychotherapy | Central Institute of Mental Health | Clinic for Phychiatry and Psychotherapy | |
| We are studying neurodegenerative diseases and synaptic transmission disorders, in particular Alzheimers disease. To this end we use a combination of state of the art approaches including primary neuronal cultures, organotypic cultures and animal models. In this regard we have developped inducible KO and KI models of the amlyloid precursor protein APP and for the related APLPs. More recently we started to leverage the physiological functions of secreted neurotrophic APPs fragments for Alzheimer treatment. | | Institute of Pharmacy and Molecular Biotechnology | |
| immune regulation in brain tumors, development of therapeutic strategies for the immunotherapy of gliomas and other types of cancer with a focus on adaptive immunity | Heidelberg University Hospital | | |
| neuroregeneration, spinal cord injury, tissue engineering, neuroinflammation, central neuropathic pain, epigenetic regulation | Heidelberg University Hospital | Clinic for Paraplegiology | |
| neuromuscular biology, neuromuscular model systems, organoids, microscopic 3D and live cell imaging, optical tissue clearing, AI-assisted 3D image analysis | | Mannheim Center for Translational Neuroscience | |
| congenital disorders of glycosylation | Heidelberg University Hospital | Congenital Disorders of Glycosylation | |
| | Heidelberg University Hospital | Clinic for Paraplegiology | |
| brain tumors, biomarkers, neuro-cancer interaction, immunotherapy | Heidelberg University Hospital | | |
