| presynaptic terminals: from basic biology to dysregulation in brain disease | Medical Faculty Heidelberg | Institute of Anatomy and Cell Biology | |
| cellular neuroscience with a focus on glial cell physiology | Medical Faculty Heidelberg | Institute of Anatomy and Cell Biology | |
| I am interested in the cerebral organization of somatosensory processing, and especially the functional reorganization occurring after peripheral changes (e.g. amputation) or after a "virtual" brain lesion such as Transcranial magnetic stimulation (TMS). In my previous research, I have been combining TMS and functional imaging (fMRI) to map the neural plasticity in sensory areas. This combination could be useful to optimize therapeutic application of TMS in sensory-related disorders. | Central Institute of Mental Health | Cognitive and Clinical Neuroscience | |
| neuronal calcium signaling; synaptic activity-driven transcription, NMDA receptor functions in survival and cell death, neuroprotection, drug discovery | | Institute of Neurobiology | |
| magnetic resonance neurography | Heidelberg University Hospital | | |
| | | University Hospital Heidelberg | |
| neuroinflammation and neurodegeneration | Heidelberg University Hospital | | |
| impact of social relationships on health | Heidelberg University Hospital | Institute for Medical Psychology | |
| retinal degeneration, autoimmune disease, neuroinflammation, multiple sclerosis | Heidelberg University Hospital | | |
| | Central Institute of Mental Health | Neuropeptide Research in Psychiatry | |
| systems neuroscience, cortico-subcortical loops, learning, sensory processing, neurophysiology, optogenetics | Heidelberg University Hospital | Institute of Physiology and Pathophysiology | |
| | Heidelberg University Hospital | Center for Psychosocial Medicine | |
| protein quality control and neurodegeneration | | Center for Molecular Biology | |
| cellular neurosciences, brain energy metabolism, neuroinflammation, neuronal oscillations, microglia, electrophysiology | Medical Faculty Heidelberg | Institute of Physiology and Pathophysiology | |
| molecular cell biology of synapses | Medical Faculty Heidelberg | Institute for Anatomy and Cell Biology | |
| molecular mechanisms underlying chronic pain | Medical Faculty Heidelberg | Institute of Pharmacology | |
| | Medical Faculty Heidelberg | Institute for Anatomy and Cell Biology | |
| molecular and transcriptional control of neuronal morphology in health and disease | | Institute of Neurobiology | |
| psychiatry and psychotherapy | Central Institute of Mental Health | Clinic for Phychiatry and Psychotherapy | |
| | Heidelberg University Hospital | Department of Clinical Neurobiology | |
| We are studying neurodegenerative diseases and synaptic transmission disorders, in particular Alzheimers disease. To this end we use a combination of state of the art approaches including primary neuronal cultures, organotypic cultures and animal models. In this regard we have developped inducible KO and KI models of the amlyloid precursor protein APP and for the related APLPs. More recently we started to leverage the physiological functions of secreted neurotrophic APPs fragments for Alzheimer treatment. | | Institute of Pharmacy and Molecular Biotechnology | |
| immune regulation in brain tumors, development of therapeutic strategies for the immunotherapy of gliomas and other types of cancer with a focus on adaptive immunity | Heidelberg University Hospital | | |
| neuroregeneration, spinal cord injury, tissue engineering, neuroinflammation, central neuropathic pain, epigenetic regulation | Heidelberg University Hospital | Clinic for Paraplegiology | |
| neuromuscular biology, neuromuscular model systems, organoids, microscopic 3D and live cell imaging, optical tissue clearing, AI-assisted 3D image analysis | | Mannheim Center for Translational Neuroscience | |
| translational neurobiology, neuroimmunology | | Mannheim Center for Translational Neuroscience | |
| experimental pain research | | Experimental Pain Research | |
| | | Institute of Neuroanatomy | |
| reconstitution of neuronal exocytosis using purified components, biochemical and structural characterization to reveal molecular mechanisms | | Heidelberg University Biochemistry Center | |
| addiction neuroscience and comorbidities | Central Institute of Mental Health | Institute for Psychopharmacology | |
| | Heidelberg University Hospital | Clinic for Paraplegiology | |
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| mechanisms underlying the pathogenesis of multiple sclerosis (MS), neuromyelitis spectrum disorders (NMOSD), myelin oligodendrocyte glycoprotein antibody associated disease (MOGAD) and other antibody-mediated autoimmune diseases, broadening diagnostic methods in the field of CSF analysis | Heidelberg University Hospital | | |
